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PSA: WWDC 2013 tickets go on sale in one hour!

PSA WWDC 2013 tickets go on sale in one hour!

You've had a day to renew your membership, book plane tickets and beg, borrow or steal $1,600 from your neighbors. Now it's time to sit on the WWDC homepage and find out if you'll actually be able to attend Apple's annual software shindig. The tickets go on sale in just an hour, so here's a friendly heads-up that you should get a cup of coffee, charge that battery pack and practice hitting F5, just in case.

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Source: Apple

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/-qgi4F5SMN0/

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Paltrow: 'Most beautiful' title 'not true'

This cover image released by People shows actress Gwyneth Paltrow on the cover of a special double issue. The 40-year-old actress tops the magazine's annual list of the "World's Most Beautiful," announced Wednesday, April 24, 2013. Paltrow stars in the upcoming film, "Iron Man 3," out on May 3. The issue is available on newsstands on Friday, April 26. (AP Photo/People Magazine)

This cover image released by People shows actress Gwyneth Paltrow on the cover of a special double issue. The 40-year-old actress tops the magazine's annual list of the "World's Most Beautiful," announced Wednesday, April 24, 2013. Paltrow stars in the upcoming film, "Iron Man 3," out on May 3. The issue is available on newsstands on Friday, April 26. (AP Photo/People Magazine)

(AP) ? Gwyneth Paltrow says she's thrilled to be picked by People magazine as "World's Most Beautiful Woman" for 2013 but it's "obviously not true."

Paltrow questioned her own selection as she walked the red carpet at the Hollywood premiere of "Iron Man 3" Wednesday night.

"It's funny, these things, because it's like obviously not true. But it's very sweet to be named that," Paltrow told The Associated Press. "Because I mean you can't say that, you know! But it's been wonderful. It's been very wonderful. And as my friend said, it's so nice that someone who has kids and is a mom and is not like 21 is named that. It's really an honor."

Paltrow said her two children weren't aware of the news in this week's edition of the magazine, but she'd been getting plenty of congratulatory emails from friends and family.

The 40-year-old actress stars as Pepper Potts, Tony Stark's love interest and assistant-turned-business partner in the "Iron Man" trilogy. Her co-stars in "Iron Man 3" praised People's proclamation.

"Completely justified. Completely justified. She's gorgeous," said Guy Pearce.

"Let me tell you: She is as gracious and beautiful inside as she is outside. She's got a good heart. She's got a good heart. A lovely girl," said Ben Kingsley.

___

Online:

http://www.people.com/mostbeautiful

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-04-25-US-People-Paltrow/id-3613225fc81d4b7181de7d3460a20a93

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Toxicity profile informs decision on preferred conditioning regimen in autologous transplant for neuroblastoma

Apr. 24, 2013 ? The stem cell transplant regimen that was commonly used in the United States to treat advanced neuroblastoma in children appears to be more toxic than the equally effective regimen employed in Europe and Egypt, according to a new study to be presented at the 26th annual meeting of the American Society of Pediatric Hematology Oncology in Miami April 24-27. The U.S. regimen was associated with more acute toxicity to the kidneys and liver.

This and other research informed the recent decision of the Children's Oncology Group (COG) to switch to the busulfan-based regimen used for years in Europe and Egypt, said senior author Leslie E. Lehmann, MD, clinical director of pediatric stem cell transplantation at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) in Boston.

Both approaches to high-risk neuroblastoma employ high doses of chemotherapy to eradicate cancer cells followed by infusion of the patient's previously collected stem cells to allow the patient to recover more quickly and safely. Since 2007, physicians at DF/CHCC and others in the Children's Oncology Group had been using a combination of high-dose carboplatin, etoposide, and melphalan to prepare patients for transplant, said Lehmann. European centers have preferred busulfan and melphalan over the platinum-based regimen.

"We have had a long-standing collaboration with Children's Cancer Hospital Egypt in Cairo, which is under the leadership of senior author Dr. Alaa Elhaddad," Lehmann said. "We decided to compare the toxicities in patients who received care that was very similar except for the drugs used in the preparative regimen.

"We found there was no difference in survival, but our regimen was associated with more liver and kidney toxicity and more bloodstream infections," she noted. "This was very useful information as COG contemplated switching to the European approach."

In addition to the idea of using toxicity data to choose between approaches of similar efficacy, Lehmann noted, "This study demonstrates you can have true collaboration between transplant centers located in very different parts of the world."

First author of the study is Yasser Elborai, MD, of the Children's Cancer Hospital Egypt.

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The above story is reprinted from materials provided by Dana-Farber Cancer Institute, via Newswise. The original article was written by Richard Saltus.

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/Bf_324a_9io/130424140518.htm

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বৃহস্পতিবার, ২৫ এপ্রিল, ২০১৩

Activists to Obama: Stop Keystone

Power Players

Environmental activists are turning up the heat on President Obama as he faces what could be the trickiest decision of his second term: whether or not to approve the controversial proposed Keystone XL pipeline, which could reach his desk this summer.

The project, which would transport oil from the tar sands of Alberta to the Gulf of Mexico, promises jobs and energy. But critics say it will ravage the environment and send oil overseas.

?We put him in the White House because we thought he was the best chance of really making progress on the issue of climate,? the Sierrra Club?s Courtney Hight told ?Power Players.?

?He?s strongly said that he wants to do something?and this is one of his best opportunities to actually follow through,? she said.

Hight is no ordinary environmentalist. She was one of the first foot soldiers for Obama in New Hampshire in 2007 and later led his campaign?s outreach to youth voters in swing-state Florida.

In 2008, she joined the administration as a member of the president?s Council on Environmental Quality, but later quit her post disillusioned by what she saw as Obama?s weak commitment to cleaning up the earth.

?I worked for the president because I believed that he would change the way Washington fundamentally worked,? Hight said. ?It?s still important to me, and I think part of governing is that you need people to push.?

And push she has. Hight has helped to mobilized hundreds of young people to boycott the pipeline in Washington. During one protest, she was arrested in front of the White House fence.

With Obama no longer under pressure of re-election, it?s unclear what leverage Hight and fellow activists may have. Polls show a strong majority of Americans favor of approving the pipeline. It?s also backed by labor unions and business groups.

?It?s not just about denying this pipeline,? Hight said. ?It?s about, you know, making good on his investment or his promise to invest in clean energy and put that money into that, into clean energy opportunities verses into oil.?

The State Department, which is reviewing the pipeline plan, has released a favorable environmental review. However, the Environmental Protection Agency this week raised objections over the potential for harmful impacts.

What does Hight predict President Obama will do, and what are the potential consequences of his decision? Check out this episode of ?Power Players.?

ABC's Eric Wray, Alexandra Dukakis, Freda Kahen Kashi, Dick Norling, and Shari Thomas contributed to this episode.

Source: http://news.yahoo.com/blogs/power-players-abc-news/former-obama-staffer-leads-white-house-protests-against-111050839.html

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96% War Witch

All Critics (46) | Top Critics (16) | Fresh (44) | Rotten (2)

Canadian writer-director Kim Nguyen spent nearly a decade researching this docudrama about child soldiers in Africa, and the film feels as authoritative as a first-hand account.

A haunting take on unspeakably grim subject matter, shot on location in the Democratic Republic of Congo.

A powerful and upsetting portrait of a young girl compelled into unimaginably horrific circumstances.

Nguyen, astonishingly, manages to wring something vaguely like a happy ending from this tragic story.

War Witch is most effective not when we are looking in on Komona but when we are inside her head.

The powerful things we expect from "War Witch" are as advertised, but what we don't expect is even better.

You're likely to ponder its images, its insights into a very foreign (for most of us) location and the tragic situation of Komona (and others like her) for a long time to come.

Is it accurate depiction of Africa's child soldiers? I don't know, thank God. But it feels authentic to its very core, and that makes it as hard to forget as it is to ignore.

Brutal without turning exploitative, the result is harrowing and heartbreaking.

Nguyen creates a mesmerizing tone through his camerawork, editing, sound and the infusion of African folk imagery and ritual, but it's Mwanza's performance as Komona that makes "War Witch" feel so miraculous.

Nguyen reportedly worked on "War Witch" for a decade, and it shows in both the immediacy and authenticity of his tale, and the meticulous craft with which it's told.

Made with extremely clear-eyed restraint from harangues, sentiment, message-mongering, or anything else that would cheapen its central character's suffering and fight.

War Witch features a standout performance by Rachel Mwanza, but the supernatural visions don't really suit the film's tone and mood.

Nguyen's compassion and commitment to the issue is admirable, and at its best, War Witch is devastating.

War Witch is remarkable for the fact that it never strays into sentimentality or sensationalism.

...a love story between youngsters who are forced to become adults all too early in their lives.

This is a straight ahead essay on warfare at its worst and the survival of the human spirit at its best.

An astonishing drama set in Africa that vividly depicts the courage and resiliency of a 12-year-old girl whose spiritual gifts enable her to survive.

It is astonishing that film that contains such violence can have such a serene tone. The source of the serenity is the measured, calm narration by Komona (voice of Diane Umawahoro) that is the telling of her story to her unborn child

An exquisitely made film in direct contrast to the ugliness of its subject matter

The portrait of a girl who retains her dignity and strength, her faith in the future, in the face of unimaginable horrors. It's inspirational in a very real way.

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Source: http://www.rottentomatoes.com/m/war_witch/

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UN official hopeful about 2015 climate talks

DUBAI, United Arab Emirates (AP) ? Governments are more serious and the impact of climate change is more dramatic, improving chances of a groundbreaking global warming pact in 2015 in contrast with the failure of such an effort in 2009, the U.N. climate chief said Tuesday.

The climate change talks in Copenhagen were a resounding failure, setting back the movement to control global warming. Even so, the U.N. official, Christiana Figueres, is optimistic, though she admits the world needs to step up its efforts to meet its goals.

A conference is set for Bonn next week, one of a series of meetings leading up to the next major climate convention in 2015.

Briefing reporters by teleconference from Washington Tuesday, Figueres complained that no country is doing enough now, and the "scale and speed" of efforts must be intensified to ensure the world can keep temperatures from rising more than 3.6 degrees Fahrenheit (2 degrees Celsius), compared to pre-industrial times. Experts believe that meeting that target would help ensure that the worst effects of climate change can be averted.

"What is very different is that we all went to 2009 having made our own decision that governments had to come to an agreement. But there was actually no commitment of governments to come to an agreement," said Figueres, who was appointed in 2010 after serving as member of Costa Rica's negotiating team.

"It was everybody else except the governments," she said. "Now, we have commitment of countries, of governments. They have said we are going to come to agreement in 2015. They have reiterated and reemphasized that, and it is very much on track."

Noting the devastation of Hurricane Sandy and the droughts that hit the midsection of the United States last year, Figueres also said it was hard to ignore the damage caused by warming of the planet.

"Unfortunately, we have much more evidence of climate change than we did way back in 2009, and that is actually a frightening thing," she said. "It does prove negative effects of climate are accelerating, both in impact and frequency. Across the world, we have every single country being affected in some way."

Figueres also said negotiators learned from 2009 not to leave important components of the agreement to the last minute and to ensure there is "transparency (and) inclusiveness" in the talks.

Climate negotiations over the years have dogged by suspicion, with rich and poor nations accusing one another of failing to do enough to move the talks along.

"There has to be a very clear process with which we get to this agreement. We will not be going to France with 300 pages of text," she said. "The governments have decided they will engage in a very serious exercise which leads up to draft of agreement, or at least the elements of a draft agreement, by 2014."

As for the United States, Figueres said she would like to see a "high level person in the White House orchestrating" the various American efforts to combat global warming.

She said she understood the preference of the Obama administration was not to push climate change legislation through Congress, but to implement a range of executive orders to tackle climate change instead. The Obama administration has already taken such measures to set fuel efficiency standards for cars and trucks and is working on regulations for new power plants. Figueres said she hoped the U.S. would look at regulations for existing power plants as well.

A study last year from Climate Analytics, Ecofys and the Potsdam Institute for Climate Impact Research said U.S. policies won't be enough to meet its stated goal of reducing greenhouse gas emissions by 17 percent by 2020, compared to 2005 levels.

Figueres said the worldwide effort was more important than the record of a single country, even the U.S.

"Of course, the ideal scenario would be for every single of the 191 countries to come with legislation in 2015. Is that realistic? No, that is not realistic" she said. "What is important here is to very quickly for each country (to do the) maximum they can do. There is no country doing its maximum."

Source: http://news.yahoo.com/un-official-hopeful-2015-climate-talks-195618680--finance.html

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UN climate chief predicts 2015 talks won't fail

SYDNEY, April 24 (Reuters) - Australia named the following squad for the Ashes test series against England in July and August. Squad: Michael Clarke (captain), Brad Haddin (vice captain), Ed Cowan, David Warner, Phillip Hughes, Shane Watson, Usman Khawaja, Chris Rogers, Matthew Wade, Nathan Lyon, James Faulkner, Peter Siddle, Ryan Harris, James Pattinson, Mitchell Starc, Jackson Bird (Compiled by Greg Stutchbury; Editing by Peter Rutherford)

Source: http://news.yahoo.com/un-climate-chief-predicts-2015-talks-wont-fail-180604269.html

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